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Dissemination

Publications:

2025

    • Poole, S., Aning, O.A., McKee, V., Catley, T., Nielsen, A.Y., Thisgaard, H., Johansson, P., Menounou, G., Hennessy, J., Slator, C. and Gibney, A., 2025. Design and in vitr o anticancer assessment of a click chemistry-derived dinuclear copper artificial metallo-nuclease. Nucleic Acids Research, 53(1), p.gkae1250. (2025). https://doi.org/10.1093/nar/gkae1250

2024

    • Węgrzyn, E., Mejdrová, I. and Carell, T. Gradual evolution of a homo-L-peptide world on homo-D-configured RNA and DNA. Chemical Science, 15(35), pp.14171-14176. (2024) https://doi.org/10.1039/D4SC03384A
    • Gibney, A. and Kellett, A. Gene Editing with Artificial DNA Scissors. Chemistry–A European Journal, 30(57), p.e202401621. (2024) https://doi.org/10.1002/chem.202401621
    • Prieto Otoya, T.D., McQuaid, K., Hennessy, J., Menounou, G., Gibney, A., Paterson, N., Cardin, D., Kellett, A., and Cardin, C. Probing a major DNA weakness: resolving the groove and sequence selectivity of the diimine complex [Λ-Ru(phen)2phi]2+. Angew. Chem. Int. Ed. (2024). https://doi.org/10.1002/anie.202318863
    • Fleuti, M., Sanchez-Quirante, T., Poštová Slavětínská, L., Tloušt’ová, E., Tichý, M., Gurská, S., Džubák, P., Hajdúch, M., and Hocek, M. Synthesis and Biological Profiling of Quinolino-Fused 7-Deazapurine Nucleosides. ACS Omega. (2024). https://doi.org/10.1021/acsomega.4c02031
    • Prieto Otoya, T.D., McQuaid, K., Paterson, N., Cardin, D., Kellett, A., and Cardin, C. Re-pairing DNA: binding of a ruthenium phi complex to a double mismatch. Chem. Sci. (2024). https://doi.org/10.1039/D4SC01448K

2023

    • Alcalde-Ordonez, A., Barreiro-Pineiro, N., McGorman, B., Gomez-Gonzalez, J., Bouzada, D., Rivadulla, F., Vazquez, M. E., Kellett, A., Martinez-Costas, J., and Vazquez Lopez, M. A copper(ii) peptide helicate selectively cleaves DNA replication foci in mammalian cells. Chemical Science (2023). https://doi.org/10.1039/D3SC03303A
    • Dalla Pozza, M., Mesdom, P., Abdullrahman, A., Prieto Otoya, T.D., Arnoux, P., Frochot, C., Niogret, G., Saubaméa, B., Burckel, P., Hall, J., Hollenstein, M., Cardin, C.J., and Gasser, G. Increasing the π-Expansive Ligands in Ruthenium(II) Polypyridyl Complexes: Synthesis, Characterization, and Biological Evaluation for Photodynamic Therapy Applications. Inorganic Chemistry (2023). https://doi.org/10.1021/acs.inorgchem.3c02606
    • Pichler, A., Hillmeier, M., Heiss, M., Peev, E., Xefteris, S., Steigenberger, B., Thoma, I., Müller, M., Borsò, M., Imhof, A., and Carell, T. Synthesis and Structure Elucidation of Glutamyl-Queuosine. J. Am. Chem. Soc. (2023). https://doi.org/10.1021/jacs.3c10075
    • Schönegger, E.S., Crisp, A., Radukic, M., Burmester, J., Frischmuth, T. and Carell, T. Orthogonal end labelling of oligonucleotides via dual incorporation of Click reactive NTP analogues. ChemBioChem (2023). https://doi.org/10.1002/cbic.202300701
    • Hennessy, J., Klimkowski, P., Singleton, D., Gibney, A., Coche, M., Farrell, N.P., El-Sagheer, A., Brown, T. and Kellett, A. Thiazole Orange-Carboplatin Triplex-Forming Oligonucleotide (TFO) Combination Probes Enhance Targeted DNA Crosslinking. RSC Medicinal Chemistry (2023). https://doi.org/10.1039/D3MD00548H
    • Enslin, L.E, Purkait, K., Dalla Pozza, M., Saubamea, B., Mesdom, P., Visser, H.G., Gasser, G., and Schutte-Smith, M. Rhenium(I) Tricarbonyl Complexes of 1,10 Phenanthroline Derivatives with Unexpectedly High Cytotoxicity. Inorganic Chemistry (2023). https://doi.org/10.1021/acs.inorgchem.3c00730
    • Benetti, S., Dalla Pozza, M., Biancalana, L., Zacchini, S., Gasser, G., and Marchetti, F. The beneficial effect of cyclohexyl substituent on the in vitro anticancer activity of diiron vinyliminium complexes. Dalton Transactions (2023). https://doi.org/10.1039/d3dt00186e
    •  Dobrogojski, J., Nguyen, V. H., Kowalska, J., Borek, S., & Pietrowska-Borek, M. The Plasma Membrane Purinoreceptor P2K1/DORN1 Is Essential in Stomatal Closure Evoked by Extracellular Diadenosine Tetraphosphate (Ap4A) in Arabidopsis thaliana. International Journal of Molecular Sciences, 24(23), 16688. (2023) https://doi.org/10.3390/ijms242316688
    • Gibney, A., de Paiva, R.E., Singh, V., Fox, R., Thompson, D., Hennessy, J., Slator, C., McKenzie, C.J., Johansson, P., McKee, V. and Westerlund, F. A Click Chemistry‐Based Artificial Metallo‐Nuclease. Angewandte Chemie International Edition, 62(38), p.e202305759. (2023) https://doi.org/10.1002/ange.202305759
    • O’Halloran, S., Pandit, A., Heise, A. and Kellett, A. Two‐photon polymerization: fundamentals, materials, and chemical modification strategies. Advanced Science, 10(7), p.2204072. (2023) https://doi.org/10.1002/advs.202204072

2022

    • Stazzoni, S., Böhmer, D.F., Hernichel, F., Özdemir, D., Pappa, A., Drexler, D., Bauernfried, S., Witte, G., Wagner, M., Veth, S. and Hopfner, K.P. Novel Poxin Stable cGAMP‐Derivatives Are Remarkable STING Agonists. Angewandte Chemie International Edition, 61(40), p.e202207175. (2022) https://doi.org/10.1002/anie.202207175 
    • Veth, S., Fuchs, A., Özdemir, D., Dialer, C., Drexler, D.J., Knechtel, F., Witte, G., Hopfner, K.P., Carell, T. and Ploetz, E. Chemical synthesis of the fluorescent, cyclic dinucleotides cthGAMP. Chembiochem, 23(8), p.e202200005. (2022). https://doi.org/10.1002/cbic.202200005
    • Hennessy, J., McGorman, B., Molphy, Z., Farrell, N.P., Singleton, D., Brown, T. and Kellett, A. A Click Chemistry Approach to Targeted DNA Crosslinking with cis‐Platinum (II)‐Modified Triplex‐Forming Oligonucleotides. Angewandte Chemie, 134(3), p.e202110455. (2022) https://doi.org/10.1002/anie.202110455
    • Müller, F., Escobar, L., Xu, F., Wegrzyn, E., Nainyte, M., Amatov, T., Chan, C.-Y., Pichler, A., and Carell, T.  A prebiotically plausible scenario of an RNA–peptide world. Nature 605, 279–284 (2022). https://doi.org/10.1038/s41586-022-04676-3
    • Dalla Pozza, M., Abdullrahman, A., Cardin, C.J., Gasser, G., and Hall, J. Three’s a crowd – stabilisation, structure, and applications of DNA triplexes. Chemical Science (2022). https://doi.org/10.1039/D2SC01793H
    • Schönegger, E.S., Crisp, A., Müller, M., Fertl, J., Serdjukow, S., Croce, S., Kollaschinski, M., Carell, T., and Frischmuth, T. Click Chemistry Enables Rapid Amplification of Full-Length Reverse Transcripts for Long-Read Third Generation Sequencing. Bioconjugate Chemistry (2022). https://doi.org/10.1021/acs.bioconjchem.2c00353
    • Searle, B., Müller, M., Carell, T., and Kellett, A. Third Generation Sequencing of Epigenetic DNA. Angew. Chem. Int. Ed. (2022). https://doi.org/10.1002/anie.202215704
    • Schoch, S., Iacopini, D., Dalla Pozza, M., Di Pietro, S., Degano, I., Gasser, G., Di Bussolo, V., and Marchetti, F. Tethering Carbohydrates to the Vinyliminium Ligand of Antiproliferative Organometallic Diiron Complexes. Organometallics (2022). https://doi.org/10.1021/acs.organomet.1c00519
    • Galdino, A.C.M., Viganor, L., Pereira, M.M., Devereux, M., McCann, M., Branquinha, M.H., Molphy, Z., O’Carroll, S., Bain, C., Menounou, G., Kellett, A., Dos Santos, A.L.S. Copper(II) and silver(I)-1,10-phenanthroline-5,6-dione complexes interact with double-stranded DNA: further evidence of their apparent multi-modal activity towards Pseudomonas aeruginosa. J Biol Inorg Chem (2022). https://doi.org/10.1007/s00775-021-01922-3
    • Banasiak, A., Zuin Fantoni, N., Kellett, A., Colleran, J. Mapping the DNA Damaging Effects of Polypyridyl Copper Complexes with DNA Electrochemical Biosensors. Molecules, 27(3): 645 (2022). https://doi.org/10.3390/molecules27030645

2021

    • Traube, F.R., Özdemir, D., Sahin, H., Müller, M., Carell, T. et al. Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons. Nature Communications, 12, 4100. (2021). https://doi.org/10.1038/s41467-021-24353-9
    • McStay, N., Slator, C., Singh, V., Gibney, A., Westerlund, F., Kellett, A. Click and Cut: a click chemistry approach to developing oxidative DNA damaging agents, Nucleic Acids Research, Vol. 49, Issue 18: 10289–10308 (2021). https://doi.org/10.1093/nar/gkab817

2020

    • Raddaoui, N., Croce, S., Geiger, F., Borodavka, A., Möckl, L., Stazzoni, S., Viverge, B., Bräuchle, C., Frischmuth, T., Engelke, H. and Carell, T., 2020. Supersensitive Multifluorophore RNA‐FISH for Early Virus Detection and Flow‐FISH by Using Click Chemistry. ChemBioChem, 21(15), pp.2214-2218. (2020). https://doi.org/10.1002/cbic.202000081

 

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