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Dissemination

Publications:

  1. McStay, N., Slator, C., Singh, V., Gibney, A., Westerlund, F., Kellett, A. Click and Cut: a click chemistry approach to developing oxidative DNA damaging agents, Nucleic Acids Research, Vol. 49, Issue 18: 10289–10308 (2021). https://doi.org/10.1093/nar/gkab817
  2. Traube, F.R., Özdemir, D., Sahin, H., Müller, M., Carell, T. et al. Redirected nuclear glutamate dehydrogenase supplies Tet3 with α-ketoglutarate in neurons. Nature Communications, 12, 4100. (2021). https://doi.org/10.1038/s41467-021-24353-9
  3. Banasiak, A., Zuin Fantoni, N., Kellett, A., Colleran, J. Mapping the DNA Damaging Effects of Polypyridyl Copper Complexes with DNA Electrochemical Biosensors. Molecules, 27(3): 645 (2022). https://doi.org/10.3390/molecules27030645
  4. Galdino, A.C.M., Viganor, L., Pereira, M.M., Devereux, M., McCann, M., Branquinha, M.H., Molphy, Z., O’Carroll, S., Bain, C., Menounou, G., Kellett, A., Dos Santos, A.L.S. Copper(II) and silver(I)-1,10-phenanthroline-5,6-dione complexes interact with double-stranded DNA: further evidence of their apparent multi-modal activity towards Pseudomonas aeruginosa. J Biol Inorg Chem (2022). https://doi.org/10.1007/s00775-021-01922-3
  5. Schoch, S., Iacopini, D., Dalla Pozza, M., Di Pietro, S., Degano, I., Gasser, G., Di Bussolo, V., and Marchetti, F. Tethering Carbohydrates to the Vinyliminium Ligand of Antiproliferative Organometallic Diiron Complexes. Organometallics (2022). https://doi.org/10.1021/acs.organomet.1c00519
  6. Müller, F., Escobar, L., Xu, F., Wegrzyn, E., Nainyte, M., Amatov, T., Chan, C.-Y., Pichler, A., and Carell, T.  A prebiotically plausible scenario of an RNA–peptide world. Nature 605, 279–284 (2022). https://doi.org/10.1038/s41586-022-04676-3
  7. Dalla Pozza, M., Abdullrahman, A., Cardin, C.J., Gasser, G., and Hall, J. Three’s a crowd – stabilisation, structure, and applications of DNA triplexes. Chemical Science (2022). https://doi.org/10.1039/D2SC01793H
  8. Schönegger, E.S., Crisp, A., Müller, M., Fertl, J., Serdjukow, S., Croce, S., Kollaschinski, M., Carell, T., and Frischmuth, T. Click Chemistry Enables Rapid Amplification of Full-Length Reverse Transcripts for Long-Read Third Generation Sequencing. Bioconjugate Chemistry (2022). https://doi.org/10.1021/acs.bioconjchem.2c00353
  9. Searle, B., Müller, M., Carell, T., and Kellett, A. Third Generation Sequencing of Epigenetic DNA. Angew. Chem. Int. Ed. (2022). https://doi.org/10.1002/anie.202215704
  10. Benetti, S., Dalla Pozza, M., Biancalana, L., Zacchini, S., Gasser, G., and Marchetti, F. The beneficial effect of cyclohexyl substituent on the in vitro anticancer activity of diiron vinyliminium complexes. Dalton Transactions (2023). https://doi.org/10.1039/d3dt00186e
  11. Enslin, L.E, Purkait, K., Dalla Pozza, M., Saubamea, B., Mesdom, P., Visser, H.G., Gasser, G., and Schutte-Smith, M. Rhenium(I) Tricarbonyl Complexes of 1,10 Phenanthroline Derivatives with Unexpectedly High Cytotoxicity. Inorganic Chemistry (2023). https://doi.org/10.1021/acs.inorgchem.3c00730
  12. Schönegger, E.S., Crisp, A., Radukic, M., Burmester, J., Frischmuth, T. and Carell, T. Orthogonal end labelling of oligonucleotides via dual incorporation of Click reactive NTP analogues. ChemBioChem (2023). https://doi.org/10.1002/cbic.202300701
  13. Hennessy, J., Klimkowski, P., Singleton, D., Gibney, A., Coche, M., Farrell, N.P., El-Sagheer, A., Brown, T. and Kellett, A. Thiazole Orange-Carboplatin Triplex-Forming Oligonucleotide (TFO) Combination Probes Enhance Targeted DNA Crosslinking. RSC Medicinal Chemistry (2023). https://doi.org/10.1039/D3MD00548H
  14. Dalla Pozza, M., Mesdom, P., Abdullrahman, A., Prieto Otoya, T.D., Arnoux, P., Frochot, C., Niogret, G., Saubaméa, B., Burckel, P., Hall, J., Hollenstein, M., Cardin, C.J., and Gasser, G. Increasing the π-Expansive Ligands in Ruthenium(II) Polypyridyl Complexes: Synthesis, Characterization, and Biological Evaluation for Photodynamic Therapy Applications. Inorganic Chemistry (2023). https://doi.org/10.1021/acs.inorgchem.3c02606
  15. Pichler, A., Hillmeier, M., Heiss, M., Peev, E., Xefteris, S., Steigenberger, B., Thoma, I., Müller, M., Borsò, M., Imhof, A., and Carell, T. Synthesis and Structure Elucidation of Glutamyl-Queuosine. J. Am. Chem. Soc. (2023). https://doi.org/10.1021/jacs.3c10075
  16. Alcalde-Ordonez, A., Barreiro-Pineiro, N., McGorman, B., Gomez-Gonzalez, J., Bouzada, D., Rivadulla, F., Vazquez, M. E., Kellett, A., Martinez-Costas, J., and Vazquez Lopez, M. A copper(ii) peptide helicate selectively cleaves DNA replication foci in mammalian cells. Chemical Science (2023). https://doi.org/10.1039/D3SC03303A
  17. Prieto Otoya, T.D., McQuaid, K., Hennessy, J., Menounou, G., Gibney, A., Paterson, N., Cardin, D., Kellett, A., and Cardin, C. Probing a major DNA weakness: resolving the groove and sequence selectivity of the diimine complex [Λ-Ru(phen)2phi]2+. Angew. Chem. Int. Ed. (2024). https://doi.org/10.1002/anie.202318863
  18. Fleuti, M., Sanchez-Quirante, T., Poštová Slavětínská, L., Tloušt’ová, E., Tichý, M., Gurská, S., Džubák, P., Hajdúch, M., and Hocek, M. Synthesis and Biological Profiling of Quinolino-Fused 7-Deazapurine Nucleosides. ACS Omega. (2024). https://doi.org/10.1021/acsomega.4c02031
  19. Prieto Otoya, T.D., McQuaid, K., Paterson, N., Cardin, D., Kellett, A., and Cardin, C. Re-pairing DNA: binding of a ruthenium phi complex to a double mismatch. Chem. Sci. (2024). https://doi.org/10.1039/D4SC01448K

Posters:

  1. Hennessy, J., Coche, M., McGormann, B., Farrell, N.P., Brown, T., and Kellett, A. A Click Chemistry Approach to cis-Platinum(II)-TFO Targeted DNA Crosslinking. Symposium on Chemistry of Nucleic Acid Components (SCNAC), Český Krumlov, Czechia, 6 June 2022. https://zenodo.org/record/6908067#.Yt_91nZBw2w
  2. Peev, E., Heiss, M., Aumer, T., Sommermann, C., and Carell, T. Metabolization and Optimization of Carbocyclic 5-Aza-2′-Deoxycytidine. Symposium on Chemistry of Nucleic Acid Components (SCNAC), Český Krumlov, Czechia, 6 June 2022. https://zenodo.org/record/6908055#.Yt_82HZBw2w
  3. Schönegger, E.S., Crisp, A., Müller, M., Carell, T., and Frischmuth, T. Click Chemistry Enables Rapid Amplification of Full-Length Reverse Transcripts for Long-Read Third Generation Sequencing. Symposium on Chemistry of Nucleic Acid Components (SCNAC), Český Krumlov, Czechia, 6 June 2022. https://zenodo.org/record/7464724#.Y6H403bMKUk
  4. Abdullrahman, A., Dalla Pozza, M., Lambert, M.C., McQuaid, K., Cardin, C.J., and Hall, J. Crystallization and structural characterization of triplexes and triplex-ligand systems using DNA X-ray crystallography. RSC Nucleic Acids Forum, London, UK, 8 July 2022. https://zenodo.org/record/6903193#.Yt7YE3ZBw2w
  5. Prieto Otoya, T.D., McQuaid, K., Paterson, N.G., Cardin, D.J., Menounou, G., Kellett, A. and Cardin, C.J. Synthetic and structural studies of ruthenium complexes as DNA major groove binders. ISABC – 16th International Symposium on Applied Bioinorganic Chemistry, Ioannina, Greece, 11-14 June 2023. https://zenodo.org/record/8061487